Combatting Neurodegenerative Disease by Advancing Research in Cellular Metabolism and Axon Maintenance


Thomas Schwarz to give keynote speech at Inaugural Symposium

Dr. Thomas Schwarz of Harvard University will be giving the keynote address at the Inaugural Symposium for the Philip and Sima Needleman Center for Neurometabolism and Axonal Therapeutics.  The symposium will be on Friday, November 15th from 1-4 p.m. in  EPNEC Seminar Room B.
Kow Essuman wins 2019 O’Leary Prize

Kow Essuman wins 2019 O’Leary Prize

Kow Essuman, a graduate student in the Milbrandt Lab, is one of two winners of the 2019 O’Leary Prize. Yesterday Kow gave a short presentation of his research at the O’Leary Prize Competition on the Medical Campus, which was enough to convince the judges that he should win the prize. Anish Mitra, and MD/PhD candidate in the Raichle […]

Gene therapy for peripheral neuropathy successful in mice

A new paper in the Journal of Experimental Medicine details the experiments led by Dr. Stefanie Geisler in collaboration with the Milbrandt and DiAntonio labs to target SARM1 using gene therapy in mice.  This is an exciting step towards possible treatments for peripheral neuropathy and other disorders involving axon breakdown.

Inaugural Symposium

The Inaugural Symposium for the Needleman Center for Neurometabolism and Axonal Therapeutics will be held

November 15, 2019 in EPNEC MAIN AUDITORIUM from 1:00-4:30 p.m.

(note location change)


David Perlmutter, MD
Jeffrey Milbrandt, MD PhD
Philip Needleman, PhD

Ghazal Ashrafi, PhD

Calcium-dependent Regulation of Mitochondrial Metabolism in Nerve Terminals

Aaron DiAntonio, MD PhD

“The SARM1 Axon Degeneration Pathway: Molecular Mechanism and Therapeutic Potential”

Rajesh Devraj, PhD – Disarm Therapeutics

“Hunting for a New Drug: Lessons from Large Pharma, Biotech, and Venture Creation”


Thomas Schwarz, PhD – Harvard University

“Moving and Removing Neuronal Mitochondria”